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Full Professor

Education and Training

Habilitation, Instituto Superior Técnico, University of Lisbon, Portugal, 1989

Post Doctoral Fellow, Massachusetts Institute of Technology, Cambridge, MA, USA, 1983-1984

PhD, Instituto Superior Técnico, University of Lisbon, Portugal, 1983

Diploma in Chemical Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 1976

Appointments

Head of the Department of Bioengineering, Instituto Superior Técnico, University of Lisbon, Portugal

Director of the Institute for Bioengineering and Biosciences, Instituto Superior Técnico, University of Lisbon, Portugal

Principal Investigator of the Stem Cell Bioengineering and Regenerative Medicine Laboratory, Instituto Superior Técnico, University of Lisbon, Portugal

Coordinator of the MIT Portugal Program PhD program in Bioengineering

Research activities

Stem Cells Research for Tissue Engineering and Regenerative Medicine; Stem Cell Bioprocessing and Manufacturing: Development of novel stem cell bioreactors and advanced bioseparation and purification processes.

Selected publications

Cabral, J.M.S:, Lobato da Silva, C. (Eds.) Bioreactors for Stem Cell Expansion and Differentiation. CRC Press, ISBN 9781498795906 (2018).

Cabral, J.M.S., Palecek, S.P. Regenerative Medicine Manufacturing. Biotechnol J. doi:10.1002/biot.201800026 (2018).

Dias, T.P, Pinto, S.N., Santos, J.I., Fernandes, T.G., Fernandes, F., Diogo, M.M., Prieto, M., Cabral, J.M.S. Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture. Biochem Biophys Res Commun 499(3):611–617 (2018).

Jalili-Firoozinezhad, S., Prantil-Baun, R., Jiang, A., Potla, R., Mammoto, T., Weaver, J.C., Ferrante, T.C., Kim, H.J., Cabral, J.M.S., Levy, O., Ingber, D.E. Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip. Cell Death Dis 9(2):223 (2018).

Miranda, C.C., Fernandes, T.G., Diogo, M.M., Cabral, J.M.S. Towards Multi-Organoid Systems for Drug Screening Applications. Bioengineering 5:49 (2018).

Miranda, C.C., Fernandes, T.G., Pinto, S.N., Prieto, M., Diogo, M.M., Cabral, J.M.S. A scale out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies. Toxicol Lett 294:51-60 (2018).

Rodrigues, C.A.V., Silva, T.P., Nogueira, D.E.S., Fernandes, T.G., Hashimura, Y., Wesselschmidt, R., Diogo, M.M., Lee, B., Cabral, J.M.S. Scalable Culture Of Human Induced Pluripotent Cells On Microcarriers Under Xeno‐Free Conditions Using Single‐Use Vertical‐Wheel™ Bioreactors. J Chem Technol Biotechnol doi:10.1002/jctb.5738 [Epub ahead of print] (2018).

Gomes-Silva, D., Mukherjee, M., Srinivasan, M., Krenciute, G., Dakhova, O., Zheng, Y.T., Cabral, J.M.S., Rooney, C.M., Orange, J.S., Brenner, M.K. Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent. Cell Rep 21(1):17-26 (2017).

Badenes, S.M., Fernandes, T.G., Miranda, C.C., Pusch-Klein, A., Haupt, S., Rodrigues, C.A.V., Diogo, M.M., Brüstle, O., Cabral, J.M.S. Long-term expansion of human induced pluripotent stem cells in a microcarrier-based dynamic system. J Chem Technol Biotechnol 92:492–503 (2017).

Rodrigues, G.M.C., Gaj, T., Adil, M.M., Wahba, J., Rao, A.T., Lorbeer, F.K., Kulkarni, R.U., Diogo, M.M., Cabral, J.M.S., Miller, E.W. Defined and scalable differentiation of human oligodendrocyte precursors from pluripotent stem cells in a 3D culture system. Stem Cell Rep 8:1770-1783 (2017).