MSc in Molecular Biology and Genetics, Faculdade de Ciências, University of Lisbon, Portugal, 2020
Postgraduate Course in Bioethics, Faculdade de Direito, University of Lisbon, Portugal, 2018
BSc in Health Science, University of Lisbon, Portugal, 2018
My work is focused on better understanding the neuronal defects underlying the pathophysiology of Angelman Syndrome (AS), a rare neurodevelopmental disorder. For that patient-specific induced pluripotent stem cells (iPSCs) are submitted to a cortical neurogenesis protocol optimized by our group in order to characterize mature AS neurons, better define the development window for epigenetic imprinting marks and identify Angelman-specific neuronal phenotypes.
Maranga, C., Vieira, A.A., Bekman, E.P., da Rocha, S.T. Induced pluripotent stem cells for modeling Angelman syndrome. in iPSCs for Modeling Central Nervous System Disorders, Birbrair, A. (ed.), Academic Press, ISBN 9780323857642 (2021).
