MBA, NOVA School of Business and Economics and CATÓLICA-LISBON, 2008
PhD in Chemical Engineering, Department of Chemical Engineering and Chemical Technology, Imperial College London, 2004
Diploma in Applied Chemistry (minor in Biotechnology), Faculty of Sciences and Technology, New University of Lisbon, 1999
My current and future research interests at the SCERG are on tailoring biomaterials to support stem cell cultivation and design of new reactors and processes for stem cells bioengineering. At the moment, I am particularly involved on (i) the manufacture of nanofiber scaffolds to mimic aspects of the extracellular matrix, promoting cell-cell and cell-material interactions and cellular adhesion, (ii) development of hierarchical scaffolds, exploring different synthetic, natural and hybrid polymers organized at different scales, (iii) using and developing electrical conductive polymers to provide electrical stimulation to cells, promoting cell differentiation, organization and communication, (iv) prototyping devices able to provide control hydrodynamic and mechanic stimuli to cells cultured on scaffold and (v) mathematical modelling of process economics on stem cell related manufacturing process.
Garrudo, F.F.F., Mikael, P.E., Rodrigues, C.A.V., Udangawa, R.W., Paradiso, P., Chapman, C.A., Hoffman, P., Colaço, R., Cabral, J.M.S., Morgado, J., Linhardt, R.J., Ferreira, F.C. Polyaniline-polycaprolactone fibers for neural applications: Electroconductivity enhanced by pseudo-doping. Mater Sci Eng C doi: 10.1016/j.msec.2020.111680 [Epub ahead of print] (2020).
Amores de Sousa, M.C., Rodrigues, C.A.V., Ferreira, I.A.F., Diogo, M.M., Linhardt, R.J., Cabral, J.M.S, Ferreira, F.C. Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation. Front Bioeng Biotechnol 8:580135 (2020).
Silva, J.C., Moura, C.S., Borrecho, G., de Matos, A.P.A., Cabral, J.M.S., Linhardt, R.J., Ferreira, F.C. Effects of glycosaminoglycan supplementation in the chondrogenic differentiation of bone marrow- and synovial- derived mesenchymal stem/stromal cells on 3D-extruded poly (ε-caprolactone) scaffolds. Int J Poly Mat Poly Biomat doi: 10.1080/00914037.2019.1706511 [Epub ahead of print] (2020).
Silva, J.C., Moura, C.S., Borrecho, G., de Matos, A.P.A., da Silva, C.L., Cabral, J.M.S., Bártolo, P.J., Linhardt, R.J., Ferreira, F.C. Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly (ε‐Caprolactone) Scaffolds. Biotechnol J 15(2):1900078 (2020).
Bandeiras, C., Cabral, J.M.S., Gabbay, R.A., Finkelstein, S.N., Ferreira, F.C. Bringing Stem Cell‐Based Therapies for Type 1 Diabetes to the Clinic: Early Insights from Bioprocess Economics and Cost‐Effectiveness Analysis. Biotechnol J 14(8):1-9 (2019).
Garrudo, F.F.F., Udangawa, R.N., Hoffman, P.R., Sordini, L., Chapman, C.A., Mikael, P.E., Ferreira, F.A., Silva, J.C., Rodrigues, C.A.V., Cabral, J.M.S., Morgado, J.M.F., Ferreira, F.C., Linhardt, R.J. Polybenzimidazole nanofibers for neural stem cell culture. Mater Today Chem 14:100185 (2019).
Bandeiras, C., Cabral, J.M.S., Finkelstein, S.F., Ferreira, F.C. Modeling biological and economic uncertainty on cell therapy manufacturing: the choice of culture media supplementation. Regen Med 13(8). doi:rme-2018-0034 (2018).
Costa, M.H.G., McDevitt, T.C., Cabral, J.M.S., da Silva, C.L., Ferreira, F.C. Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes. J Biotechnol 262:28-39 (2017).
Pires, F., Ferreira, Q., Rodrigues, C.A.V., Morgado, J., Ferreira, F.C. Neural stem cells differentiation by electrical stimulation using a cross-linked PEDOT substrate: expanding the use of biocompatible conjugated conductive polymers for neural tissue engineering. BBA-Gen Subjects 1850:1158-1168 (2015).
Hatami, J., Andrade, P.Z., de Matos, A.P.A., Djokovic, D., Lilaia, C., Ferreira, F.C., Cabral, J.M.S., da Silva, C.L. Developing a co-culture system for effective megakaryo/thrombopoiesis from umbilical cord blood hematopoietic stem/progenitor cells. Cytotherapy 17:428-442 (2015).
Poursamar, S.A., Hatami, J., Lehner, A.N., da Silva, C.L., Ferreira, F.C., Antunes, A.P.M. Gelatin Porous Scaffolds Fabricated Using a Modified Gas Foaming Technique: Characterisation and Cytotoxicity Assessment. Mater Sci Eng C 48:63-70 (2015).
Canadas, R.F., Cavalheiro, J.M.B.T., Guerreiro, J.D.T., de Almeida, M.C.M.D., Pollet, E., da Silva, C.L., da Fonseca, M.M.R., Ferreira, F.C. Polyhydroxyalkanoates: Waste glycerol upgrade into electrospun fibrous scaffolds for stem cells culture. Int J Biol Macromol 71:131-140 (2014).
