E-mail: miguelfuzeta@tecnico.ulisboa.pt
MSc in Biological Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2016
BSc in Biological Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2014
I am interested in developing innovative strategies for cancer therapeutics, relying on a bioengineering approach. I am currently developing drug delivery systems based on natural cell-derived vesicles, exosomes, originated from human mesenchymal stem/stromal cells (MSCs) for the delivery of anticancer agents.
de Almeida Fuzeta, M., Bernardes, N., Oliveira, F.D., Costa, A.C., Fernandes-Platzgummer, A., Farinha, J.P., Rodrigues, C.A.V., Jung, S., Tseng, R.-J., Milligan, W., Lee, B., Castanho, M.A.R.B., Gaspar, D., Cabral, J.M.S., da Silva, C.L. Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System. Front Cell Dev Biol 8:553444 (2020).
de Almeida Fuzeta, M., de Matos Branco, A.D., Fernandes-Platzgummer, A., da Silva, C.L., Cabral, J.M.S. Addressing the Manufacturing Challenges of Cell-Based Therapies in Advances in Biochemical Engineering/Biotechnology, Springer (2019).
de Sousa Pinto, D., Bandeiras, C., de Almeida Fuzeta, M., Rodrigues, C.A.V., Jung, S., Hashimura, Y., Tseng, R.-J., Milligan, W., Lee, B., Ferreira, F.C., da Silva, C.L., Cabral, J.M.S. [Scalable Manufacturing of Human Mesenchymal Stromal Cells in the Vertical‐Wheel™ Bioreactor System: An Experimental and Economic Approach]. Biotechnol J doi: 10.1002/biot.201800716 [Epub ahead of print] (2019).