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PhD student

Education and Training

MSc in Biotechnology, Instituto Superior T├ęcnico, University of Lisbon, Portugal, 2018

BSc in Cellular and Molecular Biology, Faculty of Science and Technology, New University of Lisbon, Portugal, 2016

Research activities

My project involves the modification of mesenchymal stromal cells derived extracellular vesicles (MSC-EVs) through their complementation with minicircle-derived RNAi molecules, which target the silencing of key players in the vascular endothelial growth factor (VEGF) regulatory pathway, aiming at developing a novel cell-free therapeutic approach for angiogenic disorders characterized by vascular overgrowth.

Selected publications

Ulpiano, C., da Silva, C.L., Monteiro, G.A. Mesenchymal Stromal Cells (MSCs): a promising tool for cell-based angiogenic therapy. Curr Gene Ther doi: 10.2174/1566523221666210917114353 [Epub ahead of print] (2021).

Silva, M., Ulpiano, C., Bernardes, N., Monteiro, G.A., da Silva, C.L. Gene delivery as a tool to improve the therapeutic features of mesenchymal stromal cells: methods and applications in Gene Delivery: Methods and Applications, Zimmer, V. (ed.), Nova Science Publishers, ISBN 9781536162684 (2019).