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The area of Stem Cell Engineering at iBB/IST has established an international track record in the Stem Cell Engineering field [1, 2], as assessed by WTEC in US on behalf of NSF, NIST and NIH. The success of stem cell manufacturing relies on safe, robust and reproducible culture conditions and cost-effective processes, including bioreactor design, bioseparation, microscale technology and process control, combined with systems biology. The development of efficient, scalable and cost-effective production processes for Stem Cells is expected to boost their applications in Cellular and Gene Therapy, Tissue Engineering, high-throughput drug screening, toxicological testing and stem cell research.

[1] WTEC-NSF/NIST/NIH International Assessment of R&D in Stem Cell Engineering report, page 240 (2013)

[2] WTEC-NSF International Assessment of Research in Biological Engineering and Manufacturing report, page 123 (2015)

SCERG (Coordinator: Joaquim M.S. Cabral) relies on a cross-disciplinary strategy combining Bioprocess Engineering with Stem Cell Biology with activities focused on three Focus Areas: (A) Biology and Engineering of Pluripotent Stem Cells; (B) Development and Manufacturing of Cellular & Molecular Therapies; and (C) Biomaterials and Devices for Advanced Medicine.

SCERG Team comprises a group of research scientists and post-graduate students with shared interests in Stem Cells, Bioprocesses, Biomaterials, Tissue Engineering and Regenerative Medicine for the diagnosis, treatment and modeling of diseases.

SCERG is organized in 7 Research Laboratories within the 3 Focus Areas.