PhD in Bioengineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2019
Visiting Scholar Researcher, Rensselaer Polytechnic Institute, USA, 2017-2018
Research Assistant, 3B's Research Group, University of Minho, Portugal, 2014-2015
MSc in Biomedical Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2013
BSc in Biomedical Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2011
- My main research interests include: i) tailoring biomaterials
structure and composition to mimic stem cell and tissue
microenvironments; ii) development of novel bio-inspired, biomimetic
and “smart” material-based strategies for regenerative medicine
applications; iii) design and prototyping of bioreactor devices for
the fabrication of tissue-engineered constructs under controlled “in
vivo-like” biophysical stimulation.
- Author of 30 original articles and 12 indexed conference abstracts
published in international peer-reviewed scientific journals, 1 book
chapter, 1 granted patent, and 18 oral and 25 poster communications
presented in relevant international scientific conference meetings
in the fields of Biomaterials and Regenerative Medicine (h-index:
12; >700 citations).
- Principal Investigator of the FCT-funded project "InSilico4OCReg:
In silico models guiding in vitro biophysical stimulation of
biomimetic hierarchical scaffolds: a computational modelling
approach towards functional osteochondral regeneration” (REF:
PTDC/EME-SIS/0838/2021.)
Santos, M.S., Carvalho, M.S., Silva, J.C. Recent Advances on Electrospun Nanofibers for Periodontal Regeneration. Nanomaterials 13(8):1307 (2023).
Miguel, F., Barbosa, F., Ferreira, F.C., Silva, J.C. Electrically Conductive Hydrogels for Articular Cartilage Tissue Engineering. Gels 8(11):710 (2022).
Barbosa, F., Ferreira, F.C., Silva, J.C. Piezoelectric electrospun fibrous scaffolds for bone, articular cartilage and osteochondral tissue engineering. Int J Mol Sci 23(6):2907 (2022).
Oliveira, A.S., Silva, J.C., Figueiredo, L., Ferreira, F.C., Kotov, N.A., Colaço, R., Serro, A.P. High-performance bilayer composites for the replacement of osteochondral defects. Biomater Sci 10:5856-5875 (2022).
Silva, J.C., Moura, C.S., Borrecho, G., Matos, A.P.A., Silva, C.L., Cabral, J.M.S., Bártolo, P.J., Linhardt, R.J., Ferreira, F.C. Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly (ε‐Caprolactone) Scaffolds. Biotechnol J doi: 10.1002/biot.201900078 [Epub ahead of print] (2019).
Silva, J.C., Udangawa, R.N., Chen, J., Mancinelli, C.D., Garrudo, F.F.F., Mikael, P.E., Cabral, J.M.S., Ferreira, F.C., Linhardt, R.J. Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering. Mater Sci Eng C 107:110291 (2020).
Carvalho, M.S., Silva, J.C., Udangawa, R.N., Cabral, J.M.S., Ferreira, F.C., da Silva, C.L., Linhardt, R.J., Vashishth, D. Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering. Mater Sci Eng C 99:479-490 (2019).
Silva, J.C., Carvalho, M.S., Udangawa, R.N., Moura, C.S., Cabral, J.M.S., da Silva, C.L., Ferreira, F.C., Vashishth, D., Linhardt, R.J. Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient‐tailored bone tissue engineering approach. J Biomed Mater Res B doi: 10.1002/jbm.b.34554 [Epub ahead of print] (2020).
Silva, J.C., Moura, C.S., Borrecho, G., de Matos, A.P.A., Cabral, J.M.S., Linhardt, R.J., Ferreira, F.C. Effects of glycosaminoglycan supplementation in the chondrogenic differentiation of bone marrow- and synovial- derived mesenchymal stem/stromal cells on 3D-extruded poly (ε-caprolactone) scaffolds. Int J Poly Mat Poly Biomat doi: 10.1080/00914037.2019.1706511 [Epub ahead of print] (2020).
Silva, J.C., Carvalho, M.S., Han, X., Xia, K., Mikael, P.E., Cabral, J.M.S., Ferreira, F.C., Linhardt, R.J. Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices. Glycoconj J 36(2):141-154 (2019).