Research Fellow, Instituto de Biologia Experimental e Tecnológica, Portugal, 2019-2020
MSc in Biomedical Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2019
BSc in Biomedical Engineering, Instituto Superior Técnico, University of Lisbon, Portugal, 2017
My work is focused on developing region-specific brain organoids derived from patient-specific human induced pluripotent stem cells (hiPSCs), capable of better capturing molecular, cellular and structural aspects of the developing human brain. I am also interested in brain organoid assembly, by fusing organoids from different brain regions in order to create more realistic models of human brain development, that can be used to capture the initial establishment of functional circuits and how these are disrupted in neurodevelopment disorders, namely Rett Syndrome.
Tenreiro, M.F., Louro, A.F., Alves, P.M., Serra, M. Next generation of heart regenerative therapies: progress and promise of cardiac tissue engineering. NPJ Regen Med 6:30 (2021).
Almeida, H.V., Tenreiro, M.F., Louro, A.F., Abecasis, B., Santinha, D., Calmeiro, T., Fortunato, E., Ferreira, L., Alves, P.M., Serra, M. Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation. ACS Appl Bio Mater 4(2):1888-1899 (2021).