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2020

Amores de Sousa, M.C., Rodrigues, C.A.V., Ferreira, I.A.F., Diogo, M.M., Linhardt, R.J., Cabral, J.M.S, Ferreira, F.C. Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation. Front Bioeng Biotechnol 8:580135 (2020).

Baltazar, T., Merola, J., Catarino, C., Xie, C.B., Kirkiles-Smith, N.C., Lee, V., Hotta, S., Dai, G., Xu, X., Ferreira, F.C., Saltzman, M., Pober, J.S., Karande, P. Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells. Tissue Eng A 26(5-6):227-238 (2020).

Branco, A., Bucar, S., Moura-Sampaio, J., Lilaia, C., Cabral, J.M.S., Fernandes-Platzgummer, A., da Silva, C.L. Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells. Front Bioeng Biotechnol 8:573282 (2020).

Branco, M.A., Cabral, J.M.S., Diogo, M.M. From Human Pluripotent Stem Cells to 3D Cardiac Microtissues: Progress, Applications and Challenges. Bioengineering 7(3):92 (2020).

Carvalho, M.S., Silva, J.C., Hoff, C.M., Cabral, J.M.S., Linhardt, R.J., da Silva, C.L., Vashishth, D. Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells. J Cell Physiol doi: 10.1002/jcp.29653 [Epub ahead of print] (2020).

de Almeida Fuzeta, M., Bernardes, N., Oliveira, F.D., Costa, A.C., Fernandes-Platzgummer, A., Farinha, J.P., Rodrigues, C.A.V., Jung, S., Tseng, R.-J., Milligan, W., Lee, B., Castanho, M.A.R.B., Gaspar, D., Cabral, J.M.S., da Silva, C.L. Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System. Front Cell Dev Biol 8:553444 (2020).

Diniz, P., Pacheco, J., Guerra-Pinto, F., Pereira, H., Ferreira, F.C., Kerkhoffs, G. Achilles tendon elongation after acute rupture: is it a problem? A systematic review. Knee Surg Sports Traumatol Arthrosc 28:4011-4030 (2020).

Diniz, P., Sousa, D.A., Batista, J.P., Abdelatif, N., Pereira, H. Diagnosis and treatment of anterior ankle impingement: state of the art. J ISAKOS 5(5):295-303 (2020).

Fernandes, C.S.M., Rodrigues, A.L., Alves, V.D., Fernandes, T.G., Pina, A.S., Roque, A.C.A. Natural Multimerization Rules the Performance of Affinity-Based Physical Hydrogels for Stem Cell Encapsulation and Differentiation. Biomacromolecules 21(8):3081-3091 (2020).

Figueiredo, L., Fonseca, R., Pinto, L.F.V., Ferreira, F.C., Almeida, A., Rodrigues, A. Strategy to improve the mechanical properties of bioabsorbable materials based on chitosan for orthopedic fixation applications. J Mech Behav Biomed Mater 103:103572 (2020).

Gomes, A.R., Fernandes, T.G., Vaz, S.H., Silva, T.P., Bekman, E.P., Xapelli, S., Duarte, S., Ghazvini, M., Gribnau, J., Muotri, A.R., Trujillo, C.A., Sebastião, A.M., Cabral, J.M.S., Diogo, M.M. Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids. Front Cell Dev Biol 8:610427 (2020).

Gomes, A.R., Sangani, N.B., Fernandes, T.G., Diogo, M.M., Curfs, L.M.G., Reutelingsperger, C.P. Extracellular Vesicles in CNS Developmental Disorders. Int J Mol Sci 21:9428 (2020).

Gopal, S., Rodrigues, A.L., Dordick, J.S. Exploiting CRISPR Cas9 in Three-Dimensional Stem Cell Cultures to Model Disease. Front Bioeng Biotechnol 8:692 (2020).

Lee, B., Borys, B.S., Kallos, M.S., Rodrigues, C.A. V., Silva, T.P., Cabral, J.M.S. Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products. Bioengineering 7(2):31 (2020).

Maranga, C., Fernandes, T.G., Bekman, E., da Rocha, S.T. Angelman syndrome: a journey through the brain. FEBS J 287(11):2154-2175 (2020).

Meneses, J., Silva, J.C., Fernandes, S.R., Datta, A., Ferreira, F.C., Moura, C., Amado, S., Alves, N., Pascoal-Faria, P. A Multimodal Stimulation Cell Culture Bioreactor for Tissue Engineering: A Numerical Modelling Approach. Polymers 12(4):940 (2020).

Miranda, C.C., Barata, T., Vaz, S.H., Ferreira, C., Quintas, A., Bekman, E.P. hiPSC-Based Model of Prenatal Exposure to Cannabinoids: Effect on Neuronal Differentiation. Front Mol Neurosci 13:119 (2020).

Moura, C.S., Silva, J.C., Faria, S., Fernandes, P.R., da Silva, C.L., Cabral, J.M.S., Linhardt, R., Bártolo, P.J., Ferreira, F.C. Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation. J Biosci Bioeng 129(6):756-764 (2020).

Nogueira, D.E.S., Rodrigues, C.A.V., Hashimura, Y., Jung, S., Lee, B., Cabral, J.M.S. Suspension Culture of Human Induced Pluripotent Stem Cells in Single-Use Vertical-Wheel™ Bioreactors Using Aggregate and Microcarrier Culture Systems. in Stem Cells and Good Manufacturing Practices, Turksen, K. (ed.), Humana Press, ISBN 9781071613276 (2020).

Pla-Palacin, I., Sánchez-Romero, N., Morini, S., Rubio-Soto, D., Baptista, P.M. Liver Tissue Engineering in Organ Tissue Engineering (D. Eberli, S. Lee & A. Traweger, Eds.), Springer, ISBN 9783030185121 (2020).

Pushp, P., Nogueira, D.E.S., Rodrigues, C.A.V., Ferreira, F.C., Cabral, J.M.S., Gupta, M.K. A Concise Review on Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Personalized Regenerative Medicine. Stem Cell Rev and Rep 17:748-776 (2020).

Pushp, P., Sahoo, B., Ferreira, F.C., Cabral, J.M.S., Fernandes-Platzgummer, A., Gupta, M.K. Functional comparison of beating cardiomyocytes differentiated from umbilical cord‐derived mesenchymal/stromal stem cells and human foreskin‐derived induced pluripotent stem cells. J Biomed Mater Res A 108(3):496-514 (2020).

Rodrigues, A.L., Fernandes, T.G., Diogo, M.M., Cabral, J.M.S., Dordick, J.S. Advanced microtechnologies for high-throughtput screening. in Engineering Strategies for Regenerative Medicine (T.G. Fernandes, M.M. Diogo & J.M.S. Cabral, Eds.), Elsevier, ISBN 9780128162217 (2020).

Silva, J.C., Carvalho, M.S., Udangawa, R.N., Moura, C.S., Cabral, J.M.S., da Silva, C.L., Ferreira, F.C., Vashishth, D., Linhardt, R.J. Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient‐tailored bone tissue engineering approach. J Biomed Mater Res B 108:2153-2166 (2020).

Silva, J.C., Carvalho, M.S., Xia, K., Cabral, J.M.S., da Silva, C.L., Ferreira, F.C., Vashishth, D., Linhardt, R.J. Glycosaminoglycan disaccharide compositional analysis of cell-derived extracellular matrices using liquid chromatography-tandem mass spectrometry. Methods Cell Biol 156:85-106 (2020).

Silva, J.C., Han, X., Silva, T.P., Xia, K., Mikael, P.E., Cabral, J.M.S., Ferreira, F.C., Linhardt, R.J. Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow−/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia. Glycoconj J 37:345-360 (2020).

Silva, J.C., Moura, C.S., Borrecho, G., de Matos, A.P.A., da Silva, C.L., Cabral, J.M.S., Bártolo, P.J., Linhardt, R.J., Ferreira, F.C. Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly (ε‐Caprolactone) Scaffolds. Biotechnol J 15(2):1900078 (2020).

Silva, J.C., Udangawa, R.N., Chen, J., Mancinelli, C.D., Garrudo, F.F.F., Mikael, P.E., Cabral, J.M.S., Ferreira, F.C., Linhardt, R.J. Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering. Mater Sci Eng C 107:110291 (2020).

Silva, M., Monteiro, G.A., Fialho, A.M., Bernardes, N., da Silva, C.L. Conditioned Medium From Azurin-Expressing Human Mesenchymal Stromal Cells Demonstrates Antitumor Activity Against Breast and Lung Cancer Cell Lines. Front Cell Dev Biol 8:471 (2020).

Silva, T.P., Bekman, E., Fernandes, T.G., Vaz, S.H., Rodrigues, C.A.V., Diogo, M.M., Cabral J.M.S., Carmo-Fonseca, M. Maturation of human pluripotent stem cell-derived cerebellar neurons in the absence of co-culture. Front Bioeng Biotechnol 8:70 (2020).

Silva, T.P., Fernandes, T.G., Nogueira, D.E.S., Rodrigues, C.A.V., Bekman, E.P., Hashimura, Y., Jung, S., Lee, B., Carmo-Fonseca, M., Cabral, J.M.S. Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining. J Vis Exp 160:e61143 (2020).